Tesamorelin is a synthetic peptide analog of growth hormone-releasing hormone (GHRH) consisting of the 44 amino acids of human GHRH with the addition of a trans-3-hexenoic acid group. This modification enhances its stability and bioavailability compared to native GHRH. Research has demonstrated Tesamorelin's ability to stimulate growth hormone secretion from the pituitary gland in a physiological, pulsatile manner. Studies have examined its effects on body composition, particularly visceral adipose tissue reduction and metabolic parameters. Tesamorelin represents an important tool for investigating GHRH signaling pathways and growth hormone physiology.